Structure of PDB 1k49 Chain A

Receptor sequence
>1k49A (length=208) Species: 148305 (Pyricularia grisea) [Search protein sequence]
NFDAIPDVIQAFKNGEFVVVLDDPSRENEADLIIAAESVTTEQMAFMVRH
SSGLICAPLTPERTTALDLPQMVGTAYTVSVDAEHPSTTTGISAHDRALA
CRMLAAPDAQPSHFRRPGHVFPLRAVAGGVRARRGHTEAGVELCRLAGKR
PVAVISEIVDDGQEVEGRAVRAAPGMLRGDECVAFARRWGLKVCTIEDMI
AHVEKTEG
3D structure
PDB1k49 Structural definition of the active site and catalytic mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase.
ChainA
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E37 D41 C66 Y94 D99 H136 H153 E174
Catalytic site (residue number reindexed from 1) E27 D31 C56 Y77 D82 H119 H136 E157
Enzyme Commision number 4.1.99.12: 3,4-dihydroxy-2-butanone-4-phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A R36 R150 G152 H153 T154 R26 R133 G135 H136 T137
BS02 SO4 A G192 M193 R195 G175 M176 R178
BS03 SO4 A R59 R188 R49 R171
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1k49, PDBe:1k49, PDBj:1k49
PDBsum1k49
PubMed11827524
UniProtQ8TG90|RIB3_PYRO7 3,4-dihydroxy-2-butanone 4-phosphate synthase (Gene Name=RIB3)

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