Structure of PDB 1k2d Chain A

Receptor sequence
>1k2dA (length=182) Species: 10090 (Mus musculus) [Search protein sequence]
IEADHVGSYGIVVYQSPGDIGQYTFEFDGDELFYVDLDKKETIWMLPEFA
QLRSFDPQGGLQNIATGKHNLGVLTKRSNSTPATNEAPQATVFPKSPVLL
GQPNTLICFVDNIFPPVINITWLRNSKSVADGVYETSFFVNRDYSFHKLS
YLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPE
3D structure
PDB1k2d Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y9 V11 F24 S53 F54 N62 T65 N69 Y9 V12 F25 S54 F55 N63 T66 N70
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1k2d, PDBe:1k2d, PDBj:1k2d
PDBsum1k2d
PubMed12150894
UniProtP14438|HA2U_MOUSE H-2 class II histocompatibility antigen, A-U alpha chain (Fragment) (Gene Name=H2-Aa)

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