Structure of PDB 1k23 Chain A

Receptor sequence
>1k23A (length=307) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MEKILIFGHQNPDTDTICSAIAYADLKNKLGFNAEPVRLGQVNGETQYAL
DYFKQESPRLVETAANEVNGVILVDHNERQQSIKDIEEVQVLEVIDHHRI
ANFETAEPLYYRAEPVGCTATILNKMYKENNVKIEKEIAGLMLSAIISDS
LLFKSPTCTDQDVAAAKELAEIAGVDAEEYGLNMLKAGADLSKKTVEELI
SLDAKEFTLGSKKVEIAQVNTVDIEDVKKRQAELEAVISKVVAEKNLDLF
LLVITDILENDSLALAIGNEAAKVEKAFNVTLENNTALLKGVVSRKKQVV
PVLTDAM
3D structure
PDB1k23 The "open" and "closed" structures of the type-C inorganic pyrophosphatases from Bacillus subtilis and Streptococcus gordonii.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.1: inorganic diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H9 D13 D75 H9 D13 D75
BS02 MN A D15 D75 H97 T119 D149 D15 D75 H97 T119 D149
Gene Ontology
Molecular Function
GO:0004427 inorganic diphosphate phosphatase activity
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1k23, PDBe:1k23, PDBj:1k23
PDBsum1k23
PubMed11697905
UniProtP37487|PPAC_BACSU Manganese-dependent inorganic pyrophosphatase (Gene Name=ppaC)

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