Structure of PDB 1k12 Chain A

Receptor sequence
>1k12A (length=158) Species: 7936 (Anguilla anguilla) [Search protein sequence]
VIPEGYTQENVAVRGKATQSAQLRGEHAANSEASNAIDGNRDSNFYHGSC
THSSGQANPWWRVDLLQVYTITSVTITNRGDCCGERISGAEINIGQHLAS
NGVNNPECSVIGSMATGETKTFHCPAPMIGRYVVTYLPTSESLHLCEVEV
NVDKPAAA
3D structure
PDB1k12 A novel fucose recognition fold involved in innate immunity.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC A F45 H52 R79 R86 F45 H52 R79 R86
BS02 CA A N35 D38 N40 S49 C146 E147 N35 D38 N40 S49 C146 E147
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0030246 carbohydrate binding
GO:0042806 fucose binding
GO:0046872 metal ion binding
Biological Process
GO:0001868 regulation of complement activation, lectin pathway
GO:0010185 regulation of cellular defense response
GO:0045088 regulation of innate immune response
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1k12, PDBe:1k12, PDBj:1k12
PDBsum1k12
PubMed12091873
UniProtQ7SIC1|FUCL_ANGAN Fucolectin

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