Structure of PDB 1k0a Chain A

Receptor sequence
>1k0aA (length=234) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLG
EHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNP
LLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYT
DEVRRVYGVVEMALAERREALVMEFDYPVWLVGDKLTIADLAFVPWNNVV
DRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE
3D structure
PDB1k0a Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A122
Catalytic site (residue number reindexed from 1) A23
Enzyme Commision number 1.11.1.9: glutathione peroxidase.
1.8.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTX A A122 P123 N124 F146 R164 V165 E180 S181 L231 W316 A23 P24 N25 F47 R65 V66 E81 S82 L132 W196
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0006808 regulation of nitrogen utilization

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Molecular Function
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Biological Process
External links
PDB RCSB:1k0a, PDBe:1k0a, PDBj:1k0a
PDBsum1k0a
PubMed11695904
UniProtP23202|URE2_YEAST Transcriptional regulator URE2 (Gene Name=URE2)

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