Structure of PDB 1jxz Chain A

Receptor sequence
>1jxzA (length=268) Species: 72586 (Pseudomonas sp. CBS3) [Search protein sequence]
YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAV
MITGAEDAFCAGFYLREIPLDKGVAGVRDHFRIAALWWQQMIHKIIRVKR
PVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYS
LARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARE
LAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHPHFMPCLTR
FLDGHRADRPQVELPAGV
3D structure
PDB1jxz Histidine 90 Function in 4-chlorobenzoyl-coenzyme A Dehalogenase Catalysis
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C61 F64 I69 A86 Q90 G113 G114 G117 A136 W137 I142 N144 D145 E230
Catalytic site (residue number reindexed from 1) C60 F63 I68 A85 Q89 G112 G113 G116 A135 W136 I141 N143 D144 E229
Enzyme Commision number 3.8.1.7: 4-chlorobenzoyl-CoA dehalogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A G49 L202 A203 A205 T207 Q210 G48 L201 A202 A204 T206 Q209
BS02 BCA A R22 H23 R24 A26 A62 F64 Y65 L66 R67 W89 G113 W137 I140 D145 T146 R21 H22 R23 A25 A61 F63 Y64 L65 R66 W88 G112 W136 I139 D144 T145
BS03 BCA A F252 R257 A258 F251 R256 A257
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018787 4-chlorobenzoyl-CoA dehalogenase activity
Biological Process
GO:0015936 coenzyme A metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1jxz, PDBe:1jxz, PDBj:1jxz
PDBsum1jxz
PubMed11695894
UniProtA5JTM5|CBADH_PSEUC 4-chlorobenzoyl coenzyme A dehalogenase

[Back to BioLiP]