Structure of PDB 1jt0 Chain A

Receptor sequence
>1jt0A (length=188) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
NLKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFKTKENLFL
EILNIEESKWQEQWKKEQIKAKTNREKFYLYNELSLTTEYYYPLQNAIIE
FYTEYYKTNSINEKMNKLENKYIDAYHVIFKEGNLNGEWSINDVNAVSKI
AANAVNGIVTFTHEQNINERIKLMNKFSQIFLNGLSKH
3D structure
PDB1jt0 Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR.
ChainA
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A L3 S34 S35 G37 N38 Y41 H42 L2 S33 S34 G36 N37 Y40 H41 PDBbind-CN: Kd=49nM
BS02 dna A T24 T25 K36 Y40 T45 K46 T23 T24 K35 Y39 T44 K45 PDBbind-CN: Kd=49nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1jt0, PDBe:1jt0, PDBj:1jt0
PDBsum1jt0
PubMed11867549
UniProtP0A0N4|QACR_STAAU HTH-type transcriptional regulator QacR (Gene Name=qacR)

[Back to BioLiP]