Structure of PDB 1jpv Chain A

Receptor sequence
>1jpvA (length=235) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
NPVHILAKKGEVAERVLVVGDPGRARLLSTLLQNPKLTNENRGFLVYTGK
YNGETVSIATHGIGGPSIAIVLEELAMLGANVFIRYGTTGALVPYINLGE
YIIVTGASYNQGGLFYQYLRDNACVASTPDFELTNKLVTSFSKRNLKYYV
GNVFSSDAFYAEDEEFVKKWSSRGNIAVEMECATLFTLSKVKGWKSATVL
VVSDNLAKGGIWITKEELEKSVMDGAKAVLDTLTS
3D structure
PDB1jpv Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H5 G21 R25 R43 E75 R86 T89 S204 D205 L207 L219
Catalytic site (residue number reindexed from 1) H4 G20 R24 R42 E74 R85 T88 S203 D204 L206 L218
Enzyme Commision number 2.4.2.1: purine-nucleoside phosphorylase.
2.4.2.28: S-methyl-5'-thioadenosine phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A G21 R86 G88 T89 G20 R85 G87 T88
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0017061 S-methyl-5-thioadenosine phosphorylase activity
Biological Process
GO:0009116 nucleoside metabolic process
GO:0009164 nucleoside catabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1jpv, PDBe:1jpv, PDBj:1jpv
PDBsum1jpv
PubMed11489901
UniProtP50389|PNPH_SACS2 Purine nucleoside phosphorylase (Gene Name=SSO2706)

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