Structure of PDB 1jpu Chain A

Receptor sequence
>1jpuA (length=361) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
AERVFISPAKYVQGKNVITKIANYLEGIGNKTVVIADEIVWKIAGHTIVN
ELKKGNIAAEEVVFSGEASRNEVERIANIARKAEAAIVIGVGGGKTLDTA
KAVADELDAYIVIVPTAASTDAPTSALSVGVFESYRFYKKNPDLVLVDTK
IIANAPPRLLASGIADALATWVEARSVIKSGGKTMAGGIPTIAAEAIAEK
CEQTLFKYGKLAYESVKAKVVTPALEAVVEANTLLSGLGFESGGLAAAHA
IHNGFTALEGEIHHLTHGEKVAFGTLVQLALEEHSQQEIERYIELYLCLD
LPVTLEDIKLKDASREDILKVAKAATAEGETIHNAFNVTADDVADAIFAA
DQYAKAYKEKH
3D structure
PDB1jpu Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase.
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D173 H256 H259 H274
Catalytic site (residue number reindexed from 1) D166 H249 H252 H267
Enzyme Commision number 1.1.1.6: glycerol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D173 H256 H274 D166 H249 H267
BS02 ZN A E268 H271 E261 H264
Gene Ontology
Molecular Function
GO:0008888 glycerol dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0046872 metal ion binding
Biological Process
GO:0006071 glycerol metabolic process
GO:0019588 anaerobic glycerol catabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1jpu, PDBe:1jpu, PDBj:1jpu
PDBsum1jpu
PubMed11566129
UniProtP32816|GLDA_GEOSE Glycerol dehydrogenase (Gene Name=gldA)

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