Structure of PDB 1jpj Chain A

Receptor sequence
>1jpjA (length=294) Species: 271 (Thermus aquaticus) [Search protein sequence]
MFQQLSARLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVARD
FVERVREEALGKQVLESLTPAEVILATVYEALKEALGGEARLPVLKDRNL
WFLVGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQRPAAREQLRLLGE
KVGVPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAGRLQIDEPLMG
ELARLKEVLGPDEVLLVLDAMTGQEALSVARAFDEKVGVTGLVLTKLDGD
ARGGAALSARHVTGKPIYFAGVSEKPEGLEPFYPERLAGRILGM
3D structure
PDB1jpj The conformation of bound GMPPNP suggests a mechanism for gating the active site of the SRP GTPase.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A Q107 G108 G110 K111 T112 T113 Q144 K246 D248 G271 S273 E274 Q107 G108 G110 K111 T112 T113 Q144 K246 D248 G271 S273 E274
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1jpj, PDBe:1jpj, PDBj:1jpj
PDBsum1jpj
PubMed11566135
UniProtO07347|SRP54_THEAQ Signal recognition particle protein (Gene Name=ffh)

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