Structure of PDB 1joc Chain A

Receptor sequence
>1jocA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
QDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQ
IKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAK
NALTPSSKKPVRVCDACFNDLQG
3D structure
PDB1joc Multivalent endosome targeting by homodimeric EEA1.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1374 C1377 C1402 C1405 C86 C89 C114 C117
BS02 ZN A C1358 C1361 C1385 C70 C73 C97
BS03 ITP A D1352 R1370 R1371 H1372 H1373 R1375 D64 R82 R83 H84 H85 R87 MOAD: Kd=24uM
PDBbind-CN: -logKd/Ki=4.62,Kd=24uM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1joc, PDBe:1joc, PDBj:1joc
PDBsum1joc
PubMed11741531
UniProtQ15075|EEA1_HUMAN Early endosome antigen 1 (Gene Name=EEA1)

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