Structure of PDB 1jl4 Chain A

Receptor sequence
>1jl4A (length=178) Species: 10090 (Mus musculus) [Search protein sequence]
HVGSYGITVYQSPGDIGQYTFEFDGDELFYVDLDKKETVWMLPEFAQLRR
FEPQGGLQNIATGKHNLEILTKRSNSTPATNEAPQATVFPKSPVLLGQPN
TLICFVDNIFPPVINITWLRNSKSVTDGVYETSFFVNRDYSFHKLSYLTF
IPSDDDIYDCKVEHWGLEEPVLKHWEPE
3D structure
PDB1jl4 Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.
ChainA
Resolution4.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y9 T11 F24 L51 R52 R53 F54 N62 T65 G66 N69 Y5 T8 F21 L48 R49 R50 F51 N59 T62 G63 N66
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1jl4, PDBe:1jl4, PDBj:1jl4
PDBsum1jl4
PubMed11535811
UniProtP01910|HA2K_MOUSE H-2 class II histocompatibility antigen, A-K alpha chain (Gene Name=H2-Aa)

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