Structure of PDB 1jk8 Chain A

Receptor sequence
>1jk8A (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
VADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRR
FRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTLG
QPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISY
LTFLPSDDEIYDCKVEHWGLDEPLLKHWEPE
3D structure
PDB1jk8 Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y9 Y22 W43 R52 R53 F58 N62 V65 L66 H68 N69 R76 Y8 Y22 W43 R52 R53 F58 N62 V65 L66 H68 N69 R76
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1jk8, PDBe:1jk8, PDBj:1jk8
PDBsum1jk8
PubMed11376336
UniProtP01909|DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (Gene Name=HLA-DQA1)

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