Structure of PDB 1jh7 Chain A

Receptor sequence
>1jh7A (length=185) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
MEEVKKDVYSVWALPDEESEPRFKKLMEALRSEFTGPRFVPHVTVAVSAY
LTADEAKKMFESACDGLKAYTATVDRVSTGTFFFQCVFLLLQTTPEVMEA
GEHCKNHFNCSTTTPYMPHLSLLYAELTEEEKKNAQEKAYTLDSSLDGLS
FRLNRLALCKTDTEDKTLETWETVAVCNLNPGSHH
3D structure
PDB1jh7 Crystal structures of the semireduced and inhibitor-bound forms of cyclic nucleotide phosphodiesterase from Arabidopsis thaliana.
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H42 T44 M117 H119 S121 Y124
Catalytic site (residue number reindexed from 1) H42 T44 M117 H119 S121 Y124
Enzyme Commision number 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UVC A S10 H42 T44 F84 H119 S121 Y124 T163 S10 H42 T44 F84 H119 S121 Y124 T163
BS02 UVC A G36 P37 R38 F39 G36 P37 R38 F39
Gene Ontology
Molecular Function
GO:0004112 cyclic-nucleotide phosphodiesterase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1jh7, PDBe:1jh7, PDBj:1jh7
PDBsum1jh7
PubMed11694509
UniProtO04147|CPD_ARATH Cyclic phosphodiesterase (Gene Name=At4g18930)

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