Structure of PDB 1ja9 Chain A

Receptor sequence

>1ja9A (length=259) Species: 148305 (Pyricularia grisea) [Search protein sequence]

SKPLAGKVALTTGAGRGIGRGIAIELGRRGASVVVNYGSSSKAAEEVVAE
LKKLGAQGVAIQADISKPSEVVALFDKAVSHFGGLDFVMSNSGMEVWCDE
LEVTQELFDKVFNLNTRGQFFVAQQGLKHCRRGGRIILTSSIAAVMTGIP
NHALYAGSKAAVEGFCRAFAVDCGAKGVTVNCIAPGGVKTDMFDENSWHY
APGGYKGMPQEKIDEGLANMNPLKRIGYPADIGRAVSALCQEESEWINGQ
VIKLTGGGI

3D structure

PDB

1ja9 A structural account of substrate and inhibitor specificity differences between two naphthol reductases.

Chain

Resolution

1.5 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	G40 S164 H175 Y178 K182 D217
Catalytic site (residue number reindexed from 1)	G17 S141 H152 Y155 K159 D194
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NDP	A	G36 R39 G40 I41 G61 S62 S63 A86 I88 N114 S115 G116 L137 T162 S164 Y178 K182 P208 G210 V211 T213 M215	G13 R16 G17 I18 G38 S39 S40 A63 I65 N91 S92 G93 L114 T139 S141 Y155 K159 P185 G187 V188 T190 M192
BS02	PYQ	A	S164 I165 Y178 G210 F216 S220 Y223 I282	S141 I142 Y155 G187 F193 S197 Y200 I259	MOAD: Ki=420nM

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0016491	oxidoreductase activity

View graph for
Molecular Function

External links

PDB	RCSB:1ja9, PDBe:1ja9, PDBj:1ja9
PDBsum	1ja9
PubMed	11467929
UniProt	Q9HFV6

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