Structure of PDB 1ja8 Chain A

Receptor sequence
>1ja8A (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]
KHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALA
KGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRD
FGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTT
GLIPLLGIDVAEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK
3D structure
PDB1ja8 Kinetic analysis of product inhibition in human manganese superoxide dismutase.
ChainA
Resolution2.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A H26 H74 D159 H163 H26 H74 D159 H163
Gene Ontology
Molecular Function
GO:0004784 superoxide dismutase activity
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process

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Molecular Function

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Biological Process
External links
PDB RCSB:1ja8, PDBe:1ja8, PDBj:1ja8
PDBsum1ja8
PubMed11580280
UniProtP04179|SODM_HUMAN Superoxide dismutase [Mn], mitochondrial (Gene Name=SOD2)

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