Structure of PDB 1j7e Chain A

Receptor sequence
>1j7eA (length=435) Species: 9606 (Homo sapiens) [Search protein sequence]
YEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTE
ACCDTRTSALSAKSCSPFPVHPGTAECCTKRKLCMAALKHQPQEFPTYVE
PTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGS
CCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIK
LAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDN
LSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPG
NTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAK
GPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTEL
AKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNI
3D structure
PDB1j7e A structural basis for the unique binding features of the human vitamin D-binding protein.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JY A V12 L31 Y32 K35 L75 S79 M107 V6 L25 Y26 K29 L60 S64 M85
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005499 vitamin D binding
GO:0090482 vitamin transmembrane transporter activity
GO:1902118 calcidiol binding
Biological Process
GO:0035461 vitamin transmembrane transport
GO:0042359 vitamin D metabolic process
GO:0051180 vitamin transport
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0043202 lysosomal lumen
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

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Biological Process
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Cellular Component
External links
PDB RCSB:1j7e, PDBe:1j7e, PDBj:1j7e
PDBsum1j7e
PubMed11799400
UniProtP02774|VTDB_HUMAN Vitamin D-binding protein (Gene Name=GC)

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