Structure of PDB 1j53 Chain A

Receptor sequence
>1j53A (length=174) Species: 562 (Escherichia coli) [Search protein sequence]
RQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLTGNNFHVYLKPDR
LVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAFDIGF
MDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDN
SKRTLHGALLDAQILAEVYLAMTG
3D structure
PDB1j53 Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D12 E14 E61 H162 D167
Catalytic site (residue number reindexed from 1) D6 E8 E55 H156 D161
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D12 E14 D167 D6 E8 D161
BS02 TMP A D12 E14 T15 M18 E61 V65 F102 D6 E8 T9 M12 E55 V59 F96
BS03 TMP A N99 S144 N93 S138
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:1j53, PDBe:1j53, PDBj:1j53
PDBsum1j53
PubMed11937058
UniProtP03007|DPO3E_ECOLI DNA polymerase III subunit epsilon (Gene Name=dnaQ)

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