Structure of PDB 1j1g Chain A

Receptor sequence
>1j1gA (length=190) Species: 3673 (Momordica charantia) [Search protein sequence]
MDSFWFVQQWPPAVCSFQKSGSCPGSGLRTFTIHGLWPQQSGTSLTNCPG
SPFDITKISHLQSQLNTLWPSVLRANNQQFWSHEWTKHGTCSESTFNQAA
YFKLAVDMRNNYDIIGALRPHAAGPNGRTKSRQAIKGFLKAKFGKFPGLR
CRTDPQTKVSYLVEVVACFAQDGSTLIDCTRDTCGANFIF
3D structure
PDB1j1g Crystal Structures of the Ribonuclease MC1 Mutants N71T and N71S in Complex with 5'-GMP: Structural Basis for Alterations in Substrate Specificity
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H34 W37 S44 E84 K87 H88
Catalytic site (residue number reindexed from 1) H34 W37 S44 E84 K87 H88
Enzyme Commision number 4.6.1.19: ribonuclease T2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5GP A Q9 H34 S71 V72 L73 F80 H83 E84 K87 Q9 H34 S71 V72 L73 F80 H83 E84 K87
BS02 5GP A S63 Q64 T67 N110 S63 Q64 T67 N110
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0016829 lyase activity
GO:0033897 ribonuclease T2 activity
Biological Process
GO:0006401 RNA catabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1j1g, PDBe:1j1g, PDBj:1j1g
PDBsum1j1g
PubMed12731868
UniProtP23540|RNMC1_MOMCH Ribonuclease MC (Gene Name=MC1)

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