Structure of PDB 1iyz Chain A

Receptor sequence
>1iyzA (length=299) Species: 274 (Thermus thermophilus) [Search protein sequence]
MKAWVLKRLGGPLELVDLPEPEAEEGEVVLRVEAVGLNFADHLMRLGAYL
TRLHPPFIPGMEVVGVVEGRRYAALVPQGGLAERVAVPKGALLPLPEGLS
PEEAAAFPVSFLTAYLALKRAQARPGEKVLVQAAAGALGTAAVQVARAMG
LRVLAAASRPEKLALPLALGAEEAATYAEVPERAKAWGGLDLVLEVRGKE
VEESLGLLAHGGRLVYIGAAEAPIPPLRLMRRNLAVLGFWLTPLLREGAL
VEEALGFLLPRLGRELRPVVGPVFPFAEAEAAFRALLDRGHTGKVVVRL
3D structure
PDB1iyz Crystal Structures of the Quinone Oxidoreductase from Thermus thermophilus HB8 and Its Complex with NADPH: Implication for NADPH and Substrate Recognition
ChainA
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.6.5.5: NADPH:quinone reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP A F39 T113 A133 G136 A137 A157 S158 K162 Y177 I217 A220 E221 F242 W243 L244 R292 F39 T113 A133 G136 A137 A157 S158 K162 Y177 I217 A220 E221 F239 W240 L241 R289
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003960 NADPH:quinone reductase activity
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:1iyz, PDBe:1iyz, PDBj:1iyz
PDBsum1iyz
PubMed12837796
UniProtQ8L3C8

[Back to BioLiP]