Structure of PDB 1ixo Chain A

Receptor sequence
>1ixoA (length=235) Species: 562 (Escherichia coli) [Search protein sequence]
AELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITVHLREDRR
HITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEEGGLD
VAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGC
YADAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNVKAIAAIPE
MHELNIGHAIIGRAVMTGLKDAVAEMKRLMLEARG
3D structure
PDB1ixo Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) N9 H12 H45 R47 R51 E72 E153 H193
Catalytic site (residue number reindexed from 1) N8 H11 H44 R46 R50 E71 E145 H185
Enzyme Commision number 2.6.99.2: pyridoxine 5'-phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G3P A N9 E72 H193 G194 N213 I214 G215 H216 N8 E71 H185 G186 N205 I206 G207 H208
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016769 transferase activity, transferring nitrogenous groups
GO:0033856 pyridoxine 5'-phosphate synthase activity
GO:0042802 identical protein binding
Biological Process
GO:0008615 pyridoxine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1ixo, PDBe:1ixo, PDBj:1ixo
PDBsum1ixo
PubMed12206776
UniProtP0A794|PDXJ_ECOLI Pyridoxine 5'-phosphate synthase (Gene Name=pdxJ)

[Back to BioLiP]