Structure of PDB 1isq Chain A

Receptor sequence
>1isqA (length=240) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
PFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDL
NLPSSIFSKYEVVEPETIGVNLDHLKKILKRGKAKDTLILKKGEENFLEI
TIQGTATRTFRVPLIDVEPELPFTAKVVVLGEVLKDAVKDASLVSDSIKF
IARENEFIMKAEGETQEVEIKLTLEDEGLLDIEVQEETKSAYGVSYLSDM
VKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPRV
3D structure
PDB1isq Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R45 V46 V47 L48 M225 P226 A244 P245 R246 V247 R44 V45 V46 L47 M218 P219 A237 P238 R239 V240
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030337 DNA polymerase processivity factor activity
Biological Process
GO:0006260 DNA replication
GO:0006272 leading strand elongation
GO:0006275 regulation of DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:1isq, PDBe:1isq, PDBj:1isq
PDBsum1isq
PubMed12296822
UniProtO73947|PCNA_PYRFU DNA polymerase sliding clamp (Gene Name=pcn)

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