Structure of PDB 1isc Chain A

Receptor sequence
>1iscA (length=192) Species: 562 (Escherichia coli) [Search protein sequence]
SFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGK
SLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASF
GSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDAT
PLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA
3D structure
PDB1isc Structure-function in Escherichia coli iron superoxide dismutase: comparisons with the manganese enzyme from Thermus thermophilus.
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H26 H73 D156 H160 H26 H73 D156 H160
BS02 AZI A H26 H30 H31 Y34 H73 H160 H26 H30 H31 Y34 H73 H160
Gene Ontology
Molecular Function
GO:0004784 superoxide dismutase activity
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0000303 response to superoxide
GO:0006801 superoxide metabolic process
GO:0019430 removal of superoxide radicals
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1isc, PDBe:1isc, PDBj:1isc
PDBsum1isc
PubMed7849024
UniProtP0AGD3|SODF_ECOLI Superoxide dismutase [Fe] (Gene Name=sodB)

[Back to BioLiP]