Structure of PDB 1ipp Chain A

Receptor sequence
>1ippA (length=162) Species: 5791 (Physarum polycephalum) [Search protein sequence]
ALTNAQILAVIDSWEETVGQFPVITHHVPLGGGLQGTLHCYEIPLAAPYG
VGFAKNGPTRWQYKRTINQVVHRWGSHTVPFLLEPDNINGKTCTASHLCH
NTRCHNPLHLCWESLDDNKGRNWCPGPNGGCVHAVVCLRQGPLYGPGATV
AGPQQRGSHFVV
3D structure
PDB1ipp DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N119
Catalytic site (residue number reindexed from 1) N118
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A A48 P49 G53 K56 N57 K65 T67 L116 A47 P48 G52 K55 N56 K64 T66 L115
BS02 dna A N57 R61 Q63 R74 G76 T95 A96 H98 L116 K120 N56 R60 Q62 R73 G75 T94 A95 H97 L115 K119
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing

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Molecular Function

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Biological Process
External links
PDB RCSB:1ipp, PDBe:1ipp, PDBj:1ipp
PDBsum1ipp
PubMed9665136
UniProtQ94702|PPO1_PHYPO Intron-encoded endonuclease I-PpoI

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