Structure of PDB 1io9 Chain A

Receptor sequence
>1io9A (length=366) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
MYDWFSEMRKKDPVYYDGNIWQVFSYRYTKEVLNNFSKFSSDLTGYHERL
EDLRNGKIRFDIPTRYTMLTSDPPLHDELRSMSADIFSPQKLQTLETFIR
ETTRSLLDSIDPREDDIVKKLAVPLPIIVISKILGLPIEDKEKFKEWSDL
VAFRLGKPGEIFELGKKYLELIGYVKDHLNSGTEVVSRVVNSNLSDIEKL
GYIILLLIAGNETTTNLISNSVIDFTRFNLWQRIREENLYLKAIEEALRY
SPPVMRTVRKTKERVKLGDQTIEEGEYVRVWIASANRDEEVFHDGEKFIP
DRNPNPHLSFGSGIHLCLGAPLARLEARIAIEEFSKRFRHIEILDTEKVP
NEVLNGYKRLVVRLKS
3D structure
PDB1io9 Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.
ChainA
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A209 E212 T214 C317 E326 L354
Catalytic site (residue number reindexed from 1) A209 E212 T214 C317 E326 L354
Enzyme Commision number 1.11.1.7: peroxidase.
1.14.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A M68 H76 R80 L205 A209 G210 T213 T214 L217 T257 R259 S309 F310 H315 C317 L318 G319 M68 H76 R80 L205 A209 G210 T213 T214 L217 T257 R259 S309 F310 H315 C317 L318 G319
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0004601 peroxidase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0140825 lactoperoxidase activity
Biological Process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1io9, PDBe:1io9, PDBj:1io9
PDBsum1io9
PubMed12237217
UniProtQ55080|CP119_SULAC Cytochrome P450 119 (Gene Name=cyp119)

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