Structure of PDB 1io4 Chain A

Receptor sequence
>1io4A (length=63) Species: 9606 (Homo sapiens) [Search protein sequence]
KHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVE
QLSRELSTLRNLF
3D structure
PDB1io4 Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R280 V285 K287 S288 R12 V17 K19 S20 PDBbind-CN: Kd=7.56nM
BS02 dna A R278 N282 R286 R289 R10 N14 R18 R21 PDBbind-CN: Kd=7.56nM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1io4, PDBe:1io4, PDBj:1io4
PDBsum1io4
PubMed11257229
UniProtP17676|CEBPB_HUMAN CCAAT/enhancer-binding protein beta (Gene Name=CEBPB)

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