Structure of PDB 1in4 Chain A

Receptor sequence
>1in4A (length=298) Species: 2336 (Thermotoga maritima) [Search protein sequence]
QFLRPKSLDEFIGQENVKKKLSLALEAAKMRGEVLDHVLLAGPPGLGKTT
LAHIIASELQTNIHVTSGPVLVKQGDMAAILTSLERGDVLFIDEIHRLNK
AVEELLYSAIEDFQIDIQPFTLVGATTRSGLLSSPLRSRFGIILELDFYT
VKELKEIIKRAASLMDVEIEDAAAEMIAKRSRGTPRIAIRLTKRVRDMLT
VVKADRINTDIVLKTMEVLNIDDEGLDEFDRKILKTIIEIYRGGPVGLNA
LAASLGVEADTLSEVYEPYLLQAGFLARTPRGRIVTEKAYKHLKYEVP
3D structure
PDB1in4 Structure and mechanism of the RuvB Holliday junction branch migration motor.
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) K64 T65 D109 T158 R217
Catalytic site (residue number reindexed from 1) K48 T49 D93 T127 R186
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R20 P21 F27 I28 G61 G63 K64 T65 T66 Y180 I188 P216 R217 R4 P5 F11 I12 G45 G47 K48 T49 T50 Y149 I157 P185 R186
Gene Ontology
Molecular Function
GO:0000400 four-way junction DNA binding
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005737 cytoplasm
GO:0048476 Holliday junction resolvase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1in4, PDBe:1in4, PDBj:1in4
PDBsum1in4
PubMed11478862
UniProtQ56313|RUVB_THEMA Holliday junction branch migration complex subunit RuvB (Gene Name=ruvB)

[Back to BioLiP]