Structure of PDB 1imx Chain A

Receptor sequence

>1imxA (length=56) Species: 9606 (Homo sapiens)

ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSTGIVDECCFRSCDLRRLE
MYCAPL

3D structure

• PDB: 1imx Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions.
• Chain: A
• Resolution: 1.82 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CPQ	A	L5 F16	L3 F14	PDBbind-CN: -logKd/Ki=3.52,Kd=300uM

Gene Ontology

Molecular Function

• GO:0005179 hormone activity
• GO:0008083 growth factor activity

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space

External links

• PDB: RCSB:1imx, PDBe:1imx, PDBj:1imx
• PDBsum: 1imx
• PubMed: 11551198
• UniProt: P05019|IGF1_HUMAN Insulin-like growth factor I (Gene Name=IGF1)