Structure of PDB 1ije Chain A

Receptor sequence
>1ijeA (length=438) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGS
FKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMI
TGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVN
KMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEAT
TNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYK
IGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPG
DNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISA
GYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFV
PSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDK
3D structure
PDB1ije Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D17 K20 S21 T72 H95
Catalytic site (residue number reindexed from 1) D14 K17 S18 T69 H92
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A G19 S21 T22 N153 K154 D156 S192 W194 G16 S18 T19 N150 K151 D153 S189 W191
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003779 actin binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
GO:0019901 protein kinase binding
GO:0043022 ribosome binding
GO:0051015 actin filament binding
GO:1904408 melatonin binding
Biological Process
GO:0001933 negative regulation of protein phosphorylation
GO:0006409 tRNA export from nucleus
GO:0006412 translation
GO:0006414 translational elongation
GO:0006417 regulation of translation
GO:0006469 negative regulation of protein kinase activity
GO:0034198 cellular response to amino acid starvation
GO:0051017 actin filament bundle assembly
Cellular Component
GO:0000329 fungal-type vacuole membrane
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005853 eukaryotic translation elongation factor 1 complex
GO:0005856 cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ije, PDBe:1ije, PDBj:1ije
PDBsum1ije
PubMed11373622
UniProtP02994|EF1A_YEAST Elongation factor 1-alpha (Gene Name=TEF1)

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