Structure of PDB 1ihy Chain A

Receptor sequence
>1ihyA (length=333) [Search protein sequence]
SKIGINGFGRIGRLVLRTALEMGAQVVAVNDPFIALEYMVYMFKYDSTHG
MFKGEVKVEDGALVVDGKKITVFNEMKPENIPWSKAGAEYIVESTGVFTT
IEKASAHFKGGAKKVIISAPSADAPMFVCGVNLEKYSKDMKVVSNASCTT
NCLAPVAKVLHENFEIVEGLMTTVHAVTATQKTVDGPSAKDWRGGRGAAQ
NIIPSSTGAAKAVGKVIPELDGKLTGMAFRVPTPNVSVVDLTVRLGKECS
YDDIKAAMKTASEGPLQGVLGYTEDDVVSCDFTGDNRSSIFDAKAGIQLS
KTFVKVVSWYDNEFGYSQRVIDLIKHMQKVDSA
3D structure
PDB1ihy Structures of D-glyceraldehyde-3-phosphate dehydrogenase complexed with coenzyme analogues.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.2.1.12: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APR A G9 R10 I11 D32 P33 F34 M77 T96 T179 A180 G9 R10 I11 D31 P32 F33 M76 T95 T178 A179 PDBbind-CN: -logKd/Ki=3.74,Ki=0.18mM
Gene Ontology
Molecular Function
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1ihy, PDBe:1ihy, PDBj:1ihy
PDBsum1ihy
PubMed12136140
UniProtP56649|G3P_PANVR Glyceraldehyde-3-phosphate dehydrogenase

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