Structure of PDB 1ih0 Chain A

Receptor sequence
>1ih0A (length=71) Species: 9606 (Homo sapiens) [Search protein sequence]
GKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDG
DKNNDGRIDYDEFLEFMKGVE
3D structure
PDB1ih0 Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D105 N107 D109 Y111 E116 D15 N17 D19 Y21 E26
BS02 CA A D141 N143 D145 R147 E152 D51 N53 D55 R57 E62
BS03 EMD A F104 L121 T124 L136 G140 I148 F153 F156 M157 V160 E161 F14 L31 T34 L46 G50 I58 F63 F66 M67 V70 E71 PDBbind-CN: -logKd/Ki=5.00,Kd=10uM
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1ih0, PDBe:1ih0, PDBj:1ih0
PDBsum1ih0
PubMed11320096
UniProtP63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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