Structure of PDB 1ig0 Chain A

Receptor sequence
>1ig0A (length=317) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
EECIENPERIKIGTDLINIRNKMNLKELIHPNEDENSTLLILNQKIDIPR
PLFYKIWKLHDLKVCADGAANRLYDYLDDDETLRIKYLPNYIIGDLDSLS
EKVYKYYRKNKVTIIKQTTQYSTDFTKCVNLISLHFNSPEFRSLISNKDN
LQSNHGIELEKGIHTLYNTMTESLVFSKVTPISLLALGGIGGRFDQTVHS
ITQLYTLSENASYFKLCYMTPTDLIFLIKKNGTLIEYDPQFRNTCIGNCG
LLPIGEATLVKETRGLKWDVKNWPTSVVTGRVSSSNRFVGDNCCFIDTKD
DIILNVEIFVDKLIDFL
3D structure
PDB1ig0 The crystal structure of yeast thiamin pyrophosphokinase.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.6.2: thiamine diphosphokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VIB A Q122 Y123 S124 T125 Q120 Y121 S122 T123
BS02 VIB A W270 S285 S286 S287 W268 S283 S284 S285
Gene Ontology
Molecular Function
GO:0004788 thiamine diphosphokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0030975 thiamine binding
Biological Process
GO:0006772 thiamine metabolic process
GO:0009229 thiamine diphosphate biosynthetic process
GO:0016310 phosphorylation
GO:0042723 thiamine-containing compound metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ig0, PDBe:1ig0, PDBj:1ig0
PDBsum1ig0
PubMed11435118
UniProtP35202|THI80_YEAST Thiamine pyrophosphokinase (Gene Name=THI80)

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