Structure of PDB 1ie8 Chain A

Receptor sequence
>1ie8A (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
LRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSVTLE
LSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEV
IMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGL
KKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCR
HPPPLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFG
3D structure
PDB1ie8 Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands.
ChainA
Resolution1.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KH1 A Y143 L227 V234 S237 I271 R274 S275 S278 W286 H305 H397 L404 Y24 L57 V64 S67 I101 R104 S105 S108 W116 H135 H224 L231
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1ie8, PDBe:1ie8, PDBj:1ie8
PDBsum1ie8
PubMed11344298
UniProtP11473|VDR_HUMAN Vitamin D3 receptor (Gene Name=VDR)

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