Structure of PDB 1ibs Chain A

Receptor sequence
>1ibsA (length=297) Species: 1423 (Bacillus subtilis) [Search protein sequence]
NLKIFSLNSNPELAKEIADIVGVQLGKCSVTRFSDGEVQINIEESIRGCD
CYIIQSTSDPVNEHIMELLIMVDALKRASAKTINIVIPYYGYARQDRKSR
EPITAKLFANLLETAGATRVIALDLHAPQIQGFFDIPIDHLMGVPILGEY
FEGKNLEDIVIVSPDHGGVTRARKLADRLKAPIAIIDKRMNIVGNIEGKT
AILIDDIIDTAGTITLAANALVENGAKEVYACCTHPVLSGPAVERINNST
IKELVVTNSIKLPEEKKIERFKQLSVGPLLAEAIIRVHEQQSVSYLF
3D structure
PDB1ibs Binding of cations in Bacillus subtilis phosphoribosyldiphosphate synthetase and their role in catalysis.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.6.1: ribose-phosphate diphosphokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A D227 T228 A229 T231 D209 T210 A211 T213
BS02 ABM A R101 Q102 R104 H135 R94 Q95 R97 H126
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process
GO:0006164 purine nucleotide biosynthetic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0016310 phosphorylation
GO:0044249 cellular biosynthetic process
Cellular Component
GO:0002189 ribose phosphate diphosphokinase complex
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:1ibs, PDBe:1ibs, PDBj:1ibs
PDBsum1ibs
PubMed11790837
UniProtP14193|KPRS_BACSU Ribose-phosphate pyrophosphokinase (Gene Name=prs)

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