Structure of PDB 1iak Chain A

Receptor sequence
>1iakA (length=182) Species: 10090 (Mus musculus) [Search protein sequence]
IEADHVGSYGITVYQSPGDIGQYTFEFDGDELFYVDLDKKETVWMLPEFA
QLRRFEPQGGLQNIATGKHNLEILTKRSNSTPATNEAPQATVFPKSPVLL
GQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFFVNRDYSFHKLS
YLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPE
3D structure
PDB1iak Crystal structure of I-Ak in complex with a dominant epitope of lysozyme.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y9 F24 R52 R53 N62 T65 G66 H68 N69 E71 I72 R76 Y9 F25 R53 R54 N63 T66 G67 H69 N70 E72 I73 R77
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1iak, PDBe:1iak, PDBj:1iak
PDBsum1iak
PubMed9529148
UniProtP01910|HA2K_MOUSE H-2 class II histocompatibility antigen, A-K alpha chain (Gene Name=H2-Aa)

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