Structure of PDB 1iaj Chain A

Receptor sequence
>1iajA (length=253) Species: 10090 (Mus musculus) [Search protein sequence]
YYYSAVERNNLMRLSQSIPFVPVPPRGEPVTVYRLEESSPSILNNSMSSW
SQLGLCAKIEFLSKEEMRRAVKVLCTWSEHDILKSGHLYIIKSFLPEVIN
TWDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHS
AGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGE
LLVLDLQGVGENLTDPSVIKAEEDAIKNFRAKHHCNSCCRKLKLPDLKRN
DYT
3D structure
PDB1iaj Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity.
ChainA
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H1751 H1808 C1810 C1814 H191 H233 C235 C239
Gene Ontology
Molecular Function
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1iaj, PDBe:1iaj, PDBj:1iaj
PDBsum1iaj
PubMed11389851
UniProtQ923J1|TRPM7_MOUSE Transient receptor potential cation channel subfamily M member 7 (Gene Name=Trpm7)

[Back to BioLiP]