Structure of PDB 1i9g Chain A

Receptor sequence
>1i9gA (length=264) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
TGPFSIGERVQLTDAKGRRYTMSLTPGAEFHTHRGSIAHDAVIGLEQGSV
VKSSNGALFLVLRPLLVDYVMSMPRGPQVIYPKDAAQIVHEGDIFPGARV
LEAGAGSGALTLSLLRAVGPAGQVISYEQRADHAEHARRNVSGCYGQPPD
NWRLVVSDLADSELPDGSVDRAVLDMLAPWEVLDAVSRLLVAGGVLMVYV
ATVTQLSRIVEALRAKQCWTEPRAWETLQRGWNVVGLAVRPQHSMRGHTA
FLVATRRLAPGAVA
3D structure
PDB1i9g Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.220: tRNA (adenine(58)-N(1))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A I83 G107 G109 S110 A112 E131 Q132 H136 D161 L162 D178 M179 I80 G104 G106 S107 A109 E128 Q129 H133 D158 L159 D175 M176
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0160107 tRNA (adenine(58)-N1)-methyltransferase activity
Biological Process
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation
Cellular Component
GO:0005886 plasma membrane
GO:0031515 tRNA (m1A) methyltransferase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1i9g, PDBe:1i9g, PDBj:1i9g
PDBsum1i9g
PubMed11554794
UniProtP9WFZ1|TRMI_MYCTU tRNA (adenine(58)-N(1))-methyltransferase TrmI (Gene Name=trmI)

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