Structure of PDB 1i6t Chain A

Receptor sequence
>1i6tA (length=175) Species: 562 (Escherichia coli) [Search protein sequence]
SLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMF
YPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVTRCRPVGVLKMTDEAG
EDAKLVAVPHSKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWV
KVEGWENAEAAKAEIVASFERAKNK
3D structure
PDB1i6t The structures of Escherichia coli inorganic pyrophosphatase complexed with Ca(2+) or CaPP(i) at atomic resolution and their mechanistic implications.
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.1: inorganic diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D65 D70 D102 D65 D70 D102
BS02 CA A D97 D102 D97 D102
BS03 POP A K29 R43 Y55 D70 Y141 K142 K29 R43 Y55 D70 Y141 K142
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004427 inorganic diphosphate phosphatase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050355 inorganic triphosphate phosphatase activity
Biological Process
GO:0006796 phosphate-containing compound metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:1i6t, PDBe:1i6t, PDBj:1i6t
PDBsum1i6t
PubMed11846572
UniProtP0A7A9|IPYR_ECOLI Inorganic pyrophosphatase (Gene Name=ppa)

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