Structure of PDB 1i5e Chain A

Receptor sequence
>1i5eA (length=208) Species: 1394 ([Bacillus] caldolyticus) [Search protein sequence]
GKVYVFDHPLIQHKLTYIRDKNTGTKEFRELVDEVATLMAFEITRDLPLE
EVEIETPVSKARAKVIAGKKLGVIPILRAGIGMVDGILKLIPAAKVGHIG
LYRDPQTLKPVEYYVKLPSDVEERDFIIVDPMLATGGSAVAAIDALKKRG
AKSIKFMCLIAAPEGVKAVETAHPDVDIYIAALDERLNDHGYIVPGLGDA
GDRLFGTK
3D structure
PDB1i5e Structure of product-bound Bacillus caldolyticus uracil phosphoribosyltransferase confirms ordered sequential substrate binding.
ChainA
Resolution3.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R104 T108 D200 D203
Catalytic site (residue number reindexed from 1) R103 T107 D199 D202
Enzyme Commision number 2.4.2.9: uracil phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U5P A D131 M133 A135 T136 G138 S139 Y193 D200 A201 D130 M132 A134 T135 G137 S138 Y192 D199 A200
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004845 uracil phosphoribosyltransferase activity
GO:0005525 GTP binding
GO:0016757 glycosyltransferase activity
Biological Process
GO:0006223 uracil salvage
GO:0008655 pyrimidine-containing compound salvage
GO:0044206 UMP salvage

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Molecular Function
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Biological Process
External links
PDB RCSB:1i5e, PDBe:1i5e, PDBj:1i5e
PDBsum1i5e
PubMed12037295
UniProtP70881|UPP_BACCL Uracil phosphoribosyltransferase (Gene Name=upp)

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