Structure of PDB 1i4f Chain A

Receptor sequence
>1i4fA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB1i4f High-resolution structure of HLA-A*0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 E63 K66 H70 T73 V76 D77 Y84 Y99 T143 K146 W147 V152 Q155 Y159 T163 W167 Y171 Y7 E63 K66 H70 T73 V76 D77 Y84 Y99 T143 K146 W147 V152 Q155 Y159 T163 W167 Y171
External links
PDB RCSB:1i4f, PDBe:1i4f, PDBj:1i4f
PDBsum1i4f
PubMed11502003
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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