Structure of PDB 1i38 Chain A

Receptor sequence
>1i38A (length=247) Species: 10116 (Rattus norvegicus) [Search protein sequence]
IFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKA
LPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFN
EYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGL
KNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAR
ELHQFAFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB1i38 Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DHT A L704 N705 L707 Q711 M745 F764 A877 F891 M895 L33 N34 L36 Q40 M74 F93 A206 F220 M224 BindingDB: IC50=3.1nM,EC50=0.97nM,Ki=0.43nM
External links
PDB RCSB:1i38, PDBe:1i38, PDBj:1i38
PDBsum1i38
PubMed11320241
UniProtP15207|ANDR_RAT Androgen receptor (Gene Name=Ar)

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