Structure of PDB 1hu8 Chain A

Receptor sequence
>1hu8A (length=186) Species: 10090 (Mus musculus) [Search protein sequence]
TYQGNYGFHLGFLQSGTAKSVMCTYSPPLNKLFCQLAKTCPVQLWVSATP
PAGSRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNL
APEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPI
LTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEE
3D structure
PDB1hu8 Crystal structure of the mouse p53 core DNA-binding domain at 2.7 A resolution.
ChainA
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H176 C235 C239 H78 C137 C141
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1hu8, PDBe:1hu8, PDBj:1hu8
PDBsum1hu8
PubMed11152481
UniProtP02340|P53_MOUSE Cellular tumor antigen p53 (Gene Name=Tp53)

[Back to BioLiP]