Structure of PDB 1hse Chain A

Receptor sequence
>1hseA (length=317) Species: 9606 (Homo sapiens) [Search protein sequence]
RSVQWCAVSQPEATKCFQWQRNMRRVRGPPVSCIKRDSPIQCIQAIAENR
ADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGS
FQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFF
SASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGA
GDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSM
AVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDS
AIGFSRVPPRIDSGLYL
3D structure
PDB1hse Mutagenesis of the histidine ligand in human lactoferrin: iron binding properties and crystal structure of the histidine-253-->methionine mutant.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A D60 Y92 Y192 M253 D57 Y89 Y189 M250
BS02 CO3 A D60 T117 R121 T122 A123 G124 Y192 D57 T114 R118 T119 A120 G121 Y189
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:1hse, PDBe:1hse, PDBj:1hse
PDBsum1hse
PubMed9003186
UniProtP02788|TRFL_HUMAN Lactotransferrin (Gene Name=LTF)

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