Structure of PDB 1hsb Chain A

Receptor sequence
>1hsbA (length=270) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDRNTRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQMMYG
CDVGSDGRFLRGYRQDAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQWRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPL
3D structure
PDB1hsb Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 N63 N66 Y99 W156 Y159 W167 Y171 Y7 N63 N66 Y99 W156 Y159 W167 Y171
BS02 ARG A D77 Y84 I95 D116 T143 K146 W147 D77 Y84 I95 D116 T143 K146 W147
External links
PDB RCSB:1hsb, PDBe:1hsb, PDBj:1hsb
PDBsum1hsb
PubMed1448153
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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