Structure of PDB 1hqc Chain A

Receptor sequence
>1hqcA (length=314) Species: 274 (Thermus thermophilus) [Search protein sequence]
ALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLGKTTL
AHVIAHELGVNLRVTSGPAIEKPGDLAAILANSLEEGDILFIDEIHRLSR
QAEEHLYPAMEDFVMDIVIGQGPAARTIRLELPRFTLIGATTRPGLITAP
LLSRFGIVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGRRSRGTM
RVAKRLFRRVRDFAQVAGEEVITRERALEALAALGLDELGLEKRDREILE
VLILRFGGGPVGLATLATALSEDPGTLEEVHEPYLIRQGLLKRTPRGRVP
TELAYRHLGYPPPV
3D structure
PDB1hqc Crystal structure of the Holliday junction migration motor protein RuvB from Thermus thermophilus HB8.
ChainA
Resolution3.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K51 T52 D97 T146 R205
Catalytic site (residue number reindexed from 1) K47 T48 D93 T142 R201
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE A Y14 I15 Y10 I11
Gene Ontology
Molecular Function
GO:0000400 four-way junction DNA binding
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005737 cytoplasm
GO:0048476 Holliday junction resolvase complex

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Cellular Component
External links
PDB RCSB:1hqc, PDBe:1hqc, PDBj:1hqc
PDBsum1hqc
PubMed11171970
UniProtQ5SL87|RUVB_THET8 Holliday junction branch migration complex subunit RuvB (Gene Name=ruvB)

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