Structure of PDB 1hgg Chain A

Receptor sequence
>1hggA (length=328) Species: 132504 (Influenza A virus (A/X-31(H3N2))) [Search protein sequence]
QDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGK
ICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPY
DVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSR
LNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTNQEQTSLYVQASG
RVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGN
LIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKI
TYGACPKYVKQNTLKLATGMRNVPEKQT
3D structure
PDB1hgg Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAL A W222 G225 W222 G225
BS02 SIA A Y98 G135 S136 N137 W153 H183 E190 S228 Y98 G135 S136 N137 W153 H183 E190 S228
BS03 BGC A S95 Y100 S95 Y100
BS04 SIA A E89 Y105 R109 R269 E89 Y105 R109 R269
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1hgg, PDBe:1hgg, PDBj:1hgg
PDBsum1hgg
PubMed1327122
UniProtP03437|HEMA_I68A0 Hemagglutinin (Gene Name=HA)

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