Structure of PDB 1hg5 Chain A

Receptor sequence
>1hg5A (length=263) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTT
NSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGY
DMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTV
PIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINL
LEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLS
QAPSSLLDALEQH
3D structure
PDB1hg5 Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IHP A K28 K38 K40 H41 K10 K20 K22 H23
Gene Ontology
Molecular Function
GO:0005543 phospholipid binding
GO:0005545 1-phosphatidylinositol binding
GO:0030276 clathrin binding
Biological Process
GO:0048268 clathrin coat assembly
GO:0072583 clathrin-dependent endocytosis
Cellular Component
GO:0030136 clathrin-coated vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1hg5, PDBe:1hg5, PDBj:1hg5
PDBsum1hg5
PubMed11161218
UniProtO55012|PICAL_RAT Phosphatidylinositol-binding clathrin assembly protein (Gene Name=Picalm)

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