Structure of PDB 1hes Chain A

Receptor sequence
>1hesA (length=256) Species: 10116 (Rattus norvegicus) [Search protein sequence]
IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSG
MPECKFGMNDKIKQSIAIDDCTFHQCVRLSERSISFIPPDGEFELMRYRT
TKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLN
TSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK
KWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSG
IYETRC
3D structure
PDB1hes A Third Specificity-Determining Site in Mu 2 Adaptin for Sequences Upstream of Yxx Phi Sorting Motifs
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A D176 Q318 E391 V392 P393 K420 W421 V422 R423 D18 Q139 E212 V213 P214 K241 W242 V243 R244
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process

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Cellular Component
External links
PDB RCSB:1hes, PDBe:1hes, PDBj:1hes
PDBsum1hes
PubMed11247301
UniProtP84092|AP2M1_RAT AP-2 complex subunit mu (Gene Name=Ap2m1)

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