Structure of PDB 1hcx Chain A

Receptor sequence
>1hcxA (length=127) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
GSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATGW
KKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTG
WYYLKPDGTLADRPEFTVEPDGLITVK
3D structure
PDB1hcx A Novel Solenoid Fold in the Cell Wall Anchoring Domain of the Pneumococcal Virulence Factor Lyta
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 TPT A W241 W248 Y264 Y269 M278 D298 W50 W57 Y73 Y78 M87 D107
BS02 CHT A F199 W206 E254 F8 W15 E63
BS03 CHT A W220 W228 K274 E275 W29 W37 K83 E84
BS04 CHT A W261 W268 Y293 W70 W77 Y102
External links
PDB RCSB:1hcx, PDBe:1hcx, PDBj:1hcx
PDBsum1hcx
PubMed11694890
UniProtP06653|ALYS_STRPN Autolysin (Gene Name=lytA)

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