Structure of PDB 1h8t Chain A

Receptor sequence
>1h8tA (length=289) Species: 12078 (Echovirus E11) [Search protein sequence]
GDVVEAVENAVARVADTIGSGPSNSQAVPALTAVETGHTSQVTPSDTVQT
RHVKNYHSRSESSIENFLSRSACVYMGEYHTTNSDQTKLFASWTISARRM
VQMRRKLEIFTYVRFDVEVTFVITSKQDQGTQLGQDMPPLTHQIMYIPPG
GPIPKSVTDYTWQTSTNPSIFWTEGNAPPRMSIPFISIGNAYSNFYDGWS
HFSQNGVYGYNTLNHMGQIYVRHVNGSSPLPMTSTVRMYFKPKHVKAWVP
RPPRLCQYKNASTVNFSPTDITDKRNSITYIPDTVKPDV
3D structure
PDB1h8t Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 DOA A I95 Y192 M216 I95 Y192 M216
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1h8t, PDBe:1h8t, PDBj:1h8t
PDBsum1h8t
PubMed12097583
UniProtQ8JKE8

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